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Correction: Apamin Does Not Inhibit Human Cardiac Na+ Current, L-type Ca2+ Current or Other Major K+ Currents

  • The PLOS ONE Staff

Correction: Apamin Does Not Inhibit Human Cardiac Na+ Current, L-type Ca2+ Current or Other Major K+ Currents

  • The PLOS ONE Staff
PLOS
x
  • Published: July 30, 2014
  • DOI: 10.1371/journal.pone.0104445

There are errors in the published article. In the Results, and in the Abstract, all numbers appearing in square parentheses are data numbers, not reference numbers, and should not be hyperlinked to references.

There are errors in Figures 1 and 4. The y-axis is missing from the graphs in Figure 1(B) and in Figure 4(A) and (B). Please view the correct figures below.

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Figure 1. The endogenous K+ currents of HEK 293 cells.

(A) The representative tracing obtained with ramp protocol shown in the inset at time point indicated by arrow a in (B). The pipette and bath solutions are the same as the ones used in measuring ISK2. (B) The time course of ISK2 measured at 0 mV. (C) The representative tracings obtained with the pulse protocol shown in the inset with the pipette and bath solution used in measuring IKs. (D) The representative tracings obtained with the pulse protocol shown in the inset with the pipette and bath solutions used in measuring IKr, IK1 and Ito.

doi:10.1371/journal.pone.0096691.g001

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Figure 4. Effects of different concentrations of apamin on the rundown course of IKs in transfected HEK 293 cells.

(A) An observation experiment without apamin treatment showing time-dependent rundown, obtained with the pulse protocol shown in the inset with chromanol 293B at the end. (B) The representative time course of IKs treated with different concentrations of apamin. (C) The time constant (τ) of the rundown curve with (n = 10) and without (n = 3) apamin.

doi:10.1371/journal.pone.0096691.g004

Reference

  1. 1. Yu C-C, Ai T, Weiss JN, Chen P-S (2014) Apamin Does Not Inhibit Human Cardiac Na+ Current, L-type Ca2+ Current or Other Major K+ Currents. PLoS ONE 9(5): e96691 doi:10.1371/journal.pone.0096691.