Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

  • Loading metrics

Implementation of the Surgical Safety Checklist in Switzerland and Perceptions of Its Benefits: Cross-Sectional Survey

  • Stéphane Cullati ,

    Contributed equally to this work with: Stéphane Cullati, Marc-Joseph Licker

    stephane.cullati@hcuge.ch

    Affiliation Quality of care service, University Hospitals of Geneva, Geneva, Switzerland

  • Marc-Joseph Licker ,

    Contributed equally to this work with: Stéphane Cullati, Marc-Joseph Licker

    Affiliation Division of anesthesiology, University Hospitals of Geneva, Geneva, Switzerland

  • Patricia Francis,

    Affiliation Quality of care service, University Hospitals of Geneva, Geneva, Switzerland

  • Adriana Degiorgi,

    Affiliation Quality of care unit, Ente Ospedaliero Cantonale, Lugano, Switzerland

  • Paula Bezzola,

    Affiliation Patient Safety Foundation Switzerland, Zürich, Switzerland

  • Delphine S. Courvoisier,

    Affiliation Division of clinical epidemiology, University Hospitals of Geneva, Geneva, Switzerland

  • Pierre Chopard

    Affiliation Quality of care service, University Hospitals of Geneva, Geneva, Switzerland

Implementation of the Surgical Safety Checklist in Switzerland and Perceptions of Its Benefits: Cross-Sectional Survey

  • Stéphane Cullati, 
  • Marc-Joseph Licker, 
  • Patricia Francis, 
  • Adriana Degiorgi, 
  • Paula Bezzola, 
  • Delphine S. Courvoisier, 
  • Pierre Chopard
PLOS
x

Abstract

Objectives

To examine the implementation of the Surgical Safety Checklist (SSC) among surgeons and anaesthetists working in Swiss hospitals and clinics and their perceptions of the SSC.

Methods

Cross-sectional survey at the 97th Annual Meeting of the Swiss Society of Surgery, Switzerland, 2010. Opinions of the SSC were assessed with a 6-item questionnaire.

Results

152 respondents answered the questionnaire (participation rate 35.1%). 64.7% respondents acknowledged having a checklist in their hospital or their clinic. Median implementation year was 2009. More than 8 out of 10 respondents reported their team applied the Sign In and the Time Out very often or quasi systematically, whereas almost half of respondents acknowledged the Sign Out was applied never or rarely. The majority of respondents agreed that the checklist improves safety and team communication, and helps to develop a safety culture. However, they were less supportive about the opinion that the checklist facilitates teamwork and eliminates social hierarchy between caregivers.

Conclusions

This survey indicates that the SSC has been largely implemented in many Swiss hospitals and clinics. Both surgeons and anaesthetists perceived the SSC as a valuable tool in improving intraoperative patient safety and communication among health care professionals, with lesser importance in facilitating teamwork (and eliminating hierarchical categories).

Introduction

In Switzerland, over 1 million operations are carried out annually and major complications are expected to occur in 3 to 20% of patients with a mortality rate between 0.8 and 1.5% [1]. Although surgical procedures are performed to save lives and to improve patient's quality of life, unsafe practice and medical errors have also been incriminated in causing serious complications. Such preventable complications have been estimated to increase the total hospital cost by an average 10% [2].

With the increasing burden of patients' comorbidities [3][6], the complexity of the surgical operation and application of advanced technologies, the achievement and maintenance of clinical excellence has become increasingly challenging. Many lessons have been learned from the aviation industry where checklists and training in crew resource management have largely contributed to decrease the incidence of accidents and strengthen safety culture [7][9].

In 2007, the World Health Organization (WHO) initiated the Safer Surgery Saves Lives project [10], in which standards for the safe delivery of surgical care and a 19-item Surgical Safety Checklist (SSC) were developed [11]. This SSC encompasses the three phases of any operation that mirror the take-off cruise and landing phases of the aviation-industry. Before anaesthesia induction (“sign in”), the team confirms patient identity, surgical site, anaesthetic concerns, allergies and estimated surgical blood losses. Before skin incision (“time out”), the entire team is introduced, the anticipated critical events are reviewed, sterility and antibiotic administration is confirmed, and, imaging and other diagnostic elements are displayed if appropriate. Before the patient leaves the operating room (OR) (“sign out”), the swab count is confirmed, procedure name and handling of specific tissue/fluid specimen is confirmed and, equipment, postoperative treatment and patient destination are addressed. This SSC was trialled in eight different countries, representing a wide spectrum of health care systems and environments. Using a pre-post-design and including more than 8'000 patients, the implementation of the SSC resulted in a 30% reduction in operative mortality and major complications, in both high and low income countries [12]. A meta-analysis confirmed the effectiveness of the SSC for mortality (relative risk (RR) 0.57, 95% confidence interval (CI): 0.42–0.76) and complications (RR 0.63, 95% CI 0.58–0.67) [13], however the risk of bias remains elevated considering the large number of low quality studies, as noted in two systematic reviews [13], [14].

Acknowledging the positive impact the SSC could have on patient safety, the UK National Patient Safety Agency issued an alert stating that the SSC (in its modified version) should be completed for every surgical patient from February 2010 onwards [15]. Likewise, national health regulatory authorities in France [16] and Ireland [17] endorsed the mandatory use of SSC for all patients undergoing surgery. In other Western countries, professional health organisations for surgical care have recommended the routine utilization of SSC [18]. In Switzerland, the Patient Safety Foundation has dealt with safety issues and quality of care since 2003 and a recent survey among directors of surgery departments reported that the SSC was used in 74% of hospitals [19]. However, despite an “official” adhesion to SSC of the majority of perioperative health care professionals [20][23], there are many barriers hindering the success of its implementation [24] and the promotion of a true safety culture [20], [22], [23], [25][30]. A recent survey among Swiss surgical healthcare professionals showed moderate satisfaction with the SSC [31]. This mixed picture suggests that the implementation of the checklist is facing not only barriers from healthcare organizations but also barriers related to the perception of the benefit of the SSC. We know little about perceptions of the SSC among Swiss surgeons and anaesthetists.

The objective of this study was twofold: to report on the initial implementation of SSC among Swiss hospitals and to describe personal opinions of surgeons and anaesthetists towards the SSC.

Methods

Setting and design

The study was initiated in 2010 by a multidisciplinary team including anaesthetists, surgeons, a psychologist, a sociologist and clinical quality officers from the University Hospital of Geneva, in collaboration with the Swiss Patient Safety Foundation in Zurich. A comprehensive questionnaire was developed to address various aspects of the SSC: its implementation in the respondent's hospital/clinic, self-reported compliance and general perceptions of the SSC. The questionnaire was designed to provide a comprehensive view of the application and the attitude towards the SSC among practicing Swiss surgeons and anaesthetists. The questionnaire was translated in German, French and Italian. Each translation was conducted by two native translators and pre-tested.

The questionnaire was distributed to all participants of the joint meeting of the Swiss Society of Surgery and the Swiss Society of Anaesthesia and Reanimation that was held during the 97th Annual Meeting of the Swiss Society of Surgery in Interlaken in June 2010 (26th–28th). The purpose of the cross-sectional survey was addressed in an explanatory letter and presented by the chairman of the plenary lecture. Questionnaires were distributed by bilingual medical students, along with a Swiss chocolate to attendees agreeing to participate. No consent was asked to an Institutional Review Board because the survey was administered during a congress and no identifying information was asked to respondents.

Variables of interest (outcome)

Implementation of the SSC.

The implementation of the SSC was addressed by asking participants whether the SSC was applied in their institutions (yes, no, don't know, I don't know this surgical safety checklist), whether they received support from their administrative and clinical managing authorities (no, little, medium, strong, or very strong support) and whether different sections – Sign In, Time out, Sing Out, Others – were included in their SSC (yes, no),

Perceived compliance to the SSC.

The SSC's use was addressed with the following question: “please indicate if these checklist sections are applied either never (0%), rarely (1–29%), partially (30–59%), very often (60–90%), or quasi systematically (>90%) within your surgical/anaesthetic team (i.e., the one with which you operate most often)”. Space was also allocated for free commentary.

Perception of the SSC.

Based on the literature assessing the perception of the checklist, a list of 8 questions was built to assess the general perceptions of the SSC. Respondents had to report their agreement with each item on a scale ranging from 1 (don't agree at all) to 5 (fully agree) with an additional “No opinion” option.

Descriptive variables

The first question addressed the sector of employment (public or private) where the SSC was implemented. Sociodemographic and professional characteristics of the participants included sex, age (year of birth), profession (surgeon, anaesthetist), postgraduate training abroad (“After completing your specialist training, have you followed part of your postgraduate training in another country”? yes vs. no), type of employment (private or public sector; University or non-University hospital), workload (number of interventions performed each year) and clinical experience (number of years of clinical practice in the specialty).

Statistical analysis

Given the exploratory nature of this cross-sectional survey, no power calculation was conducted. Characteristics are presented as frequencies, means, standard deviations and medians as appropriate. To describe physician's attitude and perception regarding the SCC, the 5-point Likert scale was collapsed into a 3-point scale (positive, neutral, negative). We examined sub-groups differences with t-test if the outcome was continuous and with Chi-square test if the outcome was ordinal or dichotomous. In case of small sample size in sub-groups, we used the Fischer exact test. When a continuous outcome was not normally distributed, we used the Wilcoxon-Mann-Whitney test. The level of significance was set at p<0.05 and all tests were two-sided. All statistical analyses were completed using the SPSS software (version 18; SPSS Inc, Chicago, IL).

Results

Participants

Out of 433 questionnaires distributed at the meeting, 152 were returned (response rate 35.1%). As described in Table 1, the majority of respondents were men (62.6%), German speaking (84.2%), surgeons (61.6%) and employed in a public hospital (78.4%) with a median of 500 surgical procedures being performed annually. Their mean age was 44.5 years and, on average, they had been in practice for 16 years.

Implementation of the SSC

At the time of the survey, a SSC similar to the one proposed by the WHO was used by 65% of the respondents, the implementation being slightly higher in the public health sector than in the private sector (73% vs. 56%, respectively; p = 0.048). The median year of SSC adoption was 2009 (2007 and before, n = 5; 2008, n = 19; 2009, n = 44; 2010, n = 16; missing values, n = 68).

The implementation of the SSC within hospitals and clinics was supported by all institutional health care authorities (general management, surgery, anaesthesiology and nursing managers), although participants noted stronger support from anaesthesia departments and less support from nursing departments (Table 2). No differences were observed between the private and the public sectors.

thumbnail
Table 2. Institutional support to the implementation of the Surgical Safety Checklist (Switzerland, 2010).

https://doi.org/10.1371/journal.pone.0101915.t002

Perceived compliance to the SSC

As shown in Table 3, the “sign in” (91.5%) and “time out” (96.0%) sections of the SSC were largely included in the checklist used by respondents in their hospitals/clinics. According to respondents, the “sign in” and “time out” were completed “very often or quasi systematically” (89.9% and 82.5%, respectively). In contrast, the “sign out” was included only half the time in the checklist, and 45.2% of respondents described it as “never or rarely” completed. The proportion of “never or rarely” applied differed between the private and the public sectors (17% vs. 61%, respectively; p = 0.012). Additional sections to the WHO SCC were reported by 27% respondents, with no differences being observed between the private and the public sectors.

thumbnail
Table 3. Content of the Surgical Safety Checklist (SSC) implemented in the hospital's respondent and perceived compliance rate to the SSC (Switzerland, 2010).

https://doi.org/10.1371/journal.pone.0101915.t003

Opinions regarding the SSC and its impact

The majority of respondents agreed that the SCC was a valuable tool for improving intraoperative safety (89.5%), developing a safety culture among surgical teams (75.4%) and fostering team communication (68.8%) (Table 4). In line with these perceptions, respondents largely disagreed with the opinion that the SCC is “a waste of time” (68.8%), “brings no added value to existing safety procedures” (61.5%) and “has not demonstrated its efficacy in the scientific literature” (53.7%). Opinions were less positive for the items “SSC facilitates teamwork” and “eliminates hierarchy (during the controls) between healthcare professionals”(43.3% disagreed).

thumbnail
Table 4. Attitudes toward the Surgical Safety Checklist (Switzerland, 2010).

https://doi.org/10.1371/journal.pone.0101915.t004

Respondents who did not use the SCC tended to express more negative opinions regarding the SCC (compared to respondents using the SSC). The SSC was more often significantly perceived as “a waste of time”, “bringing no extra value to existing safety procedures”, and having “not demonstrated its efficacy in the scientific literature” (Table 5). The SCC was also more frequently perceived as “a waste of time” in the private sector than in the public sector. Age, gender, clinical experience, and training abroad did not influence judgement towards the SCC (data not shown). Likewise, attitudes towards the SCC among surgeons and anaesthetists were similar, except that anaesthetists agreed more often that the SCC eliminates interprofessional hierarchy (Table S1).

thumbnail
Table 5. Attitudes towards the SSC among respondents working in hospitals with or without the SSC and those working in the public or private sector (Switzerland, 2010).

https://doi.org/10.1371/journal.pone.0101915.t005

Discussion

Since 2007, the implementation of the SSC has achieved relative worldwide success [16], [21], [32], [33] and the objective of this study was to explore the situation in Switzerland and to answer a burning question: Is Switzerland keeping up? We found that 65% of respondents were already using a SSC in their hospital/clinic in the year of 2010, an encouraging result, suggesting that a majority of Swiss hospital and clinics are convinced of the importance of the SSC. Another Swiss survey conducted one year later (2011) found an implementation rate of 74% [19], but used another design for the questionnaire administration and was conducted among another population (directors of adult departments in operative medicine); however, this survey obtained a response rate (30%) similar to ours. More recently, a survey conducted in December 2012 among members of the Foederatio Medicorum Chirurgicorum Helvetica found an implementation rate of 79% (of a surgical checklist based on the WHO-checklist, on the Universal Protocol or other) [31], but was also impeded by a low response rate (23%). These results clearly indicate that the implementation of the SSC has evolved favourably in Switzerland; however, the low participation rate, potentially causing bias, stresses the need for additional research in this area.

Importantly, the median year of implementation was 2009. Considering that the SSC was launched worldwide in 2007 and in Europe in January 2009 [34], this suggests that most Swiss hospital and clinics have been responsive within a very short time to the campaign of “Safer Surgery Saves Lives”.

Another encouraging result is the perceived positive reaction of hospitals' authorities towards the implementation of the SSC. Indeed, institutional support was seen as globally positive, across all kinds of authorities (management, surgery, anaesthesiology, and nursing). At most, we observed differences between perceptions of managerial support in anaesthesia and nursing. In anaesthesia, the support was perceived as strong or very strong by more than nine out of ten respondents, while in nursing it was “only” two out of three. Most notably, we did not find significant differences between private and public healthcare institutions. Comparison of this result with existing literature is limited as they are few studies examining institutional support of SSC's implementation. We found only one French study showing that the SSC was supported by medical department and management in more than 80% [35].

Perceived compliance to the SSC

Most of the international literature about the compliance to the SSC in high-income countries show a relative heterogeneity: self-reported compliance rates vary between 38% and 96% [20], [23], [28], [30], [36], whereas administrative audits have shown compliance rates between 66% and 100% [26], [27], [37][40] and observational studies have shown that the SSC was initiated between 80% and 99% [24], [41][45]. But most of these compliance studies assessed the overall compliance without distinguishing the three parts of the SSC (Sign In, Time Out and Sign Out). Our results went further by assessing the compliance for each section and showed different perceived rates: almost 90% of respondents rated the SSC being applied by their surgical/anaesthetic team as “very often or quasi systematically” for the Sign In and 83% for the Time Out; however, the compliance with the Sign Out was rated applied “very often or quasi systematically” by only 47% of respondents. In other words, when implemented in hospitals and clinics, the SSC seems differently applied according to its content: before skin incision (Sign In and Time Out), the SSC seems conscientiously followed by both surgical and anaesthetic teams. However, at the end of the interventions, the compliance rate is perceived lower, a result similar to observational studies [24], [46]. This lack of compliance with the Sign Out could be rooted in the different perceptions of when to initiate this phase (toward the end of the procedure, the surgeon operator could ask to initiate the Sign Out, although the “last stitch” and the dressing might not have been completed), as noted by an observational study of team interactions during the application of the SSC [24].

Most notably, we observed no difference in compliance between the private and the public sectors. This result is discordant with a study conducted in a central American country [47], where the compliance rate was higher among private hospitals.

Although the compliance rate reported in the current study is encouraging, it should be noted that routine could reduce it over time. Indeed, a qualitative observational study assessed the compliance rate to 5 new items into the checklist already in use in an healthcare organisation and results showed that compliance rate with the introduced items was high (between 75 and 86%) –a result similar to studies examining the compliance in settings where the checklist was recently implemented [24], [41][45] – while compliance with the existing (well-established) items was relatively low (between 12% and 72%) [28].

Perceptions of the SSC

Opinions of the respondents toward the SSC are generally positive. The SSC is perceived as an instrument, that could improve patient safety in hospitals, a result similar to other studies [20], [21], [23], [48].

Some studies have pointed out that time pressures were a hindrance to compliance with the SSC, for examples in US [49] and French [26] contexts. In Switzerland, our study revealed that the SSC was not perceived as a waste of time. This is confirmed by observational studies which found that checking the items of the SSC is not time-consuming: the duration of the Time Out phase was between mean of 36[s] [24] and median of 60[s] [46].

Another barrier reported in the literature pointed out that some items of the SSC could unnecessarily duplicate existing procedures of control [26]. In our survey, more than six out of ten respondents disagreed with the opinion that the SSC brought no extra values to existing safety procedures in their hospital. This finding suggests that the SSC is perceived, overall, as a complementary tool in safety procedures rather than a duplicate.

A majority of respondents expressed the opinion that the SSC was a tool which could improve communication within the teams. According to the literature, OR teams think the SSC improves the communication within the team [20], [25], [47], [50] or between interprofessional teams [30] though some teams disagree [23], and a recent systematic review of surgical team member' perceptions concluded that the SSC was positively perceived for communication [51]. However, the real impact of the introduction of the SSC on safety communication between OR teams' member remains much less evident [52].

We expected to see differences in the perceptions of the SSC between respondents working in hospital using the SSC versus those not. Some differences were found: among respondent working without SSC, the SSC was more often perceived as a waste of time, bringing no extra value to existing safety procedures and not having demonstrated its efficacy. Differences among most other items showed the same pattern of results, but were not significant, most likely because of a lack of power to detect differences due to small sample sizes (with SSC = 97, without SSC = 48). Of notable exception, respondents working with and without SSC were both not very convinced that the SSC facilitates teamwork, and eliminates the hierarchy between healthcare providers.

Strengths and limitations

The current study did not assess barriers to the successful implementation of the SSC, a topic that has already been investigated [53]. The major limitation of our study is the low participation rate. It raises concern with the implementation and the compliance rates and with the assessment of perception agreements, which could be biased. Other Swiss studies examining the SSC [19], [31] are impeded by the same problem. We hypothesize that respondents were more interested in the SSC and our compliance rates may be overestimated. Lower than desired participation rates in surveys are common in health services research [54] and time trends suggest a decline in response rates over time [55], [56]. Nevertheless recent evidence from methodological studies indicates that non-response bias is not always systematic [57].

The topic of the present study could be potentially sensitive for some respondents and may have altered their response, causing information bias (or social desirability bias). We think that the design used for collecting data (anonymous questionnaire distributed during a congress) may have limited this effect, but it is not sure that confidentiality may affect information bias [58].

Finally, we should keep in mind that compliance with the SSC was self-reported and, thus, may have been overestimated in comparison with its actual use [59].

Conclusion

In conclusion, the implementation of the SSC in Switzerland has been largely adopted in the majority of hospitals and clinics. The perceived compliance with the SSC and the perception of the SSC are rated positively overall. As determination of prevalence could be impeded by selection bias due to low participation rate, further research should be conducted to confirm these results.

Supporting Information

Table S1.

Attitudes towards the SSC among surgeons and anesthetists.

https://doi.org/10.1371/journal.pone.0101915.s001

(DOCX)

Acknowledgments

We thank the Chairmen of the Swiss Society of Surgery and the Swiss Society of Anesthesiology and Reanimation, respectively Dr. Othmar Schöb and Dr. Tiziano Cassina, for their authorization and their support to conduct the survey at the 97th Annual Meeting of the Swiss Society of Surgery, Interlaken, 26th-28th of May 2010. We address a special thank to Dr. Valentin Neuhaus, University Hospital of Zurich, for his kind support during the data administration. The data collection during the Meeting was conducted with the help of the following medical students from the University of Geneva: Pierre Starkov, Charlotte Vitos, Nicolas Broc, Rebecca Hertzog, Milena Alec, Jennifer Rubli, Doriane Ischer. Finally, we thank Dr. Ebrahim Khabiri, University Hospital of Geneva, for his contribution during the design of the study.

Author Contributions

Conceived and designed the experiments: SC ML PF AD PB DC PC. Performed the experiments: SC ML. Analyzed the data: SC ML. Contributed reagents/materials/analysis tools: SC ML. Contributed to the writing of the manuscript: SC ML PF AD PB DC PC.

References

  1. 1. Pearse RM, Moreno RP, Bauer P, Pelosi P, Metnitz P, et al. (2012) Mortality after surgery in Europe: a 7 day cohort study. The Lancet 380: 1059–1065.
  2. 2. Fuller RL, McCullough EC, Bao MZ, Averill RF (2009) Estimating the costs of potentially preventable hospital acquired complications. Health Care Financ Rev 30: 17–32.
  3. 3. Hallett JW Jr, Textor SC, Kos PB, Nicpon G, Bower TC, et al. (1995) Advanced renovascular hypertension and renal insufficiency: trends in medical comorbidity and surgical approach from 1970 to 1993. J Vasc Surg 21: 750–759 discussion 759–760.
  4. 4. Kirksey M, Chiu YL, Ma Y, Della Valle AG, Poultsides L, et al. (2012) Trends in in-hospital major morbidity and mortality after total joint arthroplasty: United States 1998–2008. Anesth Analg 115: 321–327.
  5. 5. Malyar N, Furstenberg T, Wellmann J, Meyborg M, Luders F, et al. (2013) Recent trends in morbidity and in-hospital outcomes of in-patients with peripheral arterial disease: a nationwide population-based analysis. Eur Heart J 34: 2706–2714.
  6. 6. Millar WJ, Cole CW, Hill GB (1995) Trends in mortality and hospital morbidity due to abdominal aortic aneurysms. Health Rep 7: : 19–27, 21–30.
  7. 7. Buljac-Samardzic M, Dekker-van Doorn CM, van Wijngaarden JD, van Wijk KP (2010) Interventions to improve team effectiveness: a systematic review. Health Policy 94: 183–195.
  8. 8. Haller G, Garnerin P, Morales M-A, Pfister R, Berner M, et al. (2008) Effect of crew resource management training in a multidisciplinary obstetrical setting. International Journal for Quality in Health Care 20: 254–263.
  9. 9. Suva D, Haller G, Lübbeke A, Hoffmeyer P (2012) Differential Impact of a Crew Resource Management Program According to Professional Specialty. American Journal of Medical Quality 27: 313–320.
  10. 10. World Health Organization (2008) World Alliance For Patient Safety – Safe Surgery Saves Lives. Geneva: WHO. Available: http://www.who.int/patientsafety/safesurgery/en/index.html.
  11. 11. World Health Organization WHO Guidelines for Safe Surgery 2009. Geneva: WHO, Available: http://whqlibdoc.who.int/publications/2009/9789241598552_eng.pdf. Accessed 2009 May 11.
  12. 12. Haynes AB, Weiser TG, Berry WR, Lipsitz SR, Breizat A-HS, et al. (2009) A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population. N Engl J Med 360: 491–499.
  13. 13. Borchard A, Schwappach DL, Barbir A, Bezzola P (2012) A Systematic Review of the Effectiveness, Compliance, and Critical Factors for Implementation of Safety Checklists in Surgery. Ann Surg 256: 925–933.
  14. 14. Ko H, Turner TJ, Finnigan MA (2011) Systematic review of safety checklists for use by medical care teams in acute hospital settings - limited evidence of effectiveness. BMC Health Serv Res 11: 211.
  15. 15. NHS (2009) WHO Surgical Safety Checklist.
  16. 16. Cabarrot P, Bataillon R, Le Moign R (2011) Check-list «Sécurité du patient au bloc opératoire». Quels acquis, quelles perspectives, un an après son implantation en France. Ann Fr Anesth Reanim 30: 469–474.
  17. 17. Nugent E, Hseino H, Ryan K, Traynor O, Neary P, et al. (2013) The surgical safety checklist survey: a national perspective on patient safety. Ir J Med Sci 182: 171–176.
  18. 18. World Health Organization Global support for Safe Surgery Saves Lives Geneva: WHO: Available: http://www.who.int/patientsafety/safesurgery/endorsements_received/en/index.html. Accessed 2012 Jun 1.
  19. 19. Kaderli R, Hertig RC, Laffer U, Businger AP (2012) Surgical Safety Checklists in Operative Medicine in Switzerland. Archives of Clinical Experimental Surgery 1: 158–167.
  20. 20. Abdel-Galil K (2010) The WHO Surgical Safety Checklist: are we measuring up? Br J Oral Maxillofac Surg 48: 397–398.
  21. 21. Patterson P (2009) In survey, about half of ORs are using the WHO checklist. OR Manager 25: : 1, 6–8.
  22. 22. Fargen KM, Velat GJ, Lawson MF, Firment CS, Mocco J, .et al.. (Published Online First: 6 July 2012 doi:10.1136/neurintsurg-2012-01043) Enhanced staff communication and reduced near-miss errors with a neurointerventional procedural checklist. J Neurointerv Surg.
  23. 23. Gueguen T, Coevoet V, Mougeot M, Pierron A, Blanquart D, et al. (2011) [Deployment of the checklist “Patient safety in the operating room” in two Lorraine hospitals. Performances and difficulties]. Ann Fr Anesth Reanim 30: 489–494.
  24. 24. Cullati S, Le Du S, Raë A-C, Micallef M, Khabiri E, et al. (2013) Is the Surgical Safety Checklist successfully conducted? An observational study of social interactions in the operating rooms of a tertiary hospital. BMJ Quality & Safety 22: 639–646.
  25. 25. Bohmer AB, Wappler F, Tinschmann T, Kindermann P, Rixen D, et al. (2012) The implementation of a perioperative checklist increases patients' perioperative safety and staff satisfaction. Acta Anaesthesiol Scand 56: 332–338.
  26. 26. Fourcade A, Blache JL, Grenier C, Bourgain JL, Minvielle E (2012) Barriers to staff adoption of a surgical safety checklist. BMJ Qual Saf 21: 191–197.
  27. 27. Paugam-Burtz C, Guerrero O (2011) Check-list sécurité au bloc opératoire: le bilan après un an de déploiement à l'hôpital Beaujon. Ann Fr Anesth Reanim 30: 475–478.
  28. 28. Spence J, Goodwin B, Enns C, Dean H (2011) Student-observed surgical safety practices across an urban regional health authority. BMJ Qual Saf 20: 580–586.
  29. 29. Rodrigo-Rincón MI, Tirapu-León B, Zabalza-López P, Martín-Vizcaino MP, de La Fuente-Calixto A, et al. (2011) Percepción de los profesionales sobre la utilización y la utilidad del listado de verificación quirúrgica. Rev Calid Asist 26: 380–385.
  30. 30. Kearns RJ, Uppal V, Bonner J, Robertson J, Daniel M, et al. (2011) The introduction of a surgical safety checklist in a tertiary referral obstetric centre. BMJ Qual Saf 20: 818–822.
  31. 31. Mascherek AC, Schwappach DL, Bezzola P (2013) Frequency of use and knowledge of the WHO-surgical checklist in Swiss hospitals: a cross-sectional online survey. Patient Safety Surgery 7: 36.
  32. 32. Kelly JJ, Farley H, O'Cain C, Broida RI, Klauer K, et al. (2011) A survey of the use of time-out protocols in emergency medicine. Jt Comm J Qual Patient Saf 37: 285–288.
  33. 33. Sivathasan N, Rakowski KR, Robertson BF, Vijayarajan L (2010) The World Health Organization's ‘Surgical Safety Checklist’: should evidence-based initiatives be enforced in hospital policy? JRSM Short Rep 1: 40.
  34. 34. World Health Organization (2009) Safe Surgery Saves Lives European Workshop - 15 January 2009. Geneva: WHO. Available: http://www.who.int/patientsafety/events/09/150109/en/index.html.
  35. 35. De Thomasson E, Bonfait H, Delaunay C (2013) La check-list au bloc opératoire: quelques raisons d'espérer! Risques & qualité. 10: 156–161.
  36. 36. Makary MA, Mukherjee A, Sexton JB, Syin D, Goodrich E, et al. (2007) Operating Room Briefings and Wrong-Site Surgery. J Am Coll Surg 204: 236–243.
  37. 37. Hani D, Sedani PK, Hardee P, Bridle C, Ali N, et al. (2010) P49 Implementing of the WHO Surgical Safety Checklist' in an outpatients setting - an audit. Br J Oral Maxillofac Surg 48: S37–S37.
  38. 38. Cunat C, Flatin V, Viale JP (2011) [Implementation strategy of the HAS French surgical check-list in a university hospital]. Ann Fr Anesth Reanim 30: 484–488.
  39. 39. Rateau F, Levraut L, Colombel AL, Bernard JL, Quaranta JF, et al. (2011) [Check-list “Patient Safety” in the operating room: one year experience of 40,000 surgical procedures at the university hospital of Nice]. Ann Fr Anesth Reanim 30: 479–483.
  40. 40. Fishpool S, Pope R, Roberts C, Anthony R (2010) Re: The World Health Organisation surgical safety checklist. Clin Otolaryngol 35: 439–439.
  41. 41. Johnston G, Ekert L, Pally E (2009) Surgical Site Signing and “Time Out”: Issues of Compliance or Complacence. J Bone Joint Surg Am 91: 2577–2580.
  42. 42. Khoshbin A, Lingard L, Wright JG (2009) Evaluation of preoperative and perioperative operating room briefings at the Hospital for Sick Children. Can J Surg 52: 309–315.
  43. 43. Vats A, Vincent CA, Nagpal K, Davies RW, Darzi A, et al.. (2010) Practical challenges of introducing WHO surgical checklist: UK pilot experience. BMJ 340: : b5433-.
  44. 44. Aveling E-L, McCulloch P, Dixon-Woods M (2013) A qualitative study comparing experiences of the surgical safety checklist in hospitals in high-income and low-income countries. BMJ Open 3..
  45. 45. Rydenfält C, Johansson G, Odenrick P, Ãkerman K, Larsson PA (2013) Compliance with the WHO Surgical Safety Checklist: deviations and possible improvements. International Journal for Quality in Health Care 25: 182–187.
  46. 46. Pickering SP, Robertson ER, Griffin D, Hadi M, Morgan LJ, et al. (2013) Compliance and use of the World Health Organization checklist in UK operating theatres. British Journal of Surgery 100: 1664–1670.
  47. 47. Delgado Hurtado JJ, Jimenez X, Penalonzo MA, Villatoro C, de Izquierdo S, et al. (2012) Acceptance of the WHO Surgical Safety Checklist among surgical personnel in hospitals in Guatemala city. BMC Health Serv Res 12: 169.
  48. 48. Papaconstantinou HT, Jo C, Reznik SI, Smythe WR, Wehbe-Janek H (2013) Implementation of a surgical safety checklist: impact on surgical team perspectives. The Ochsner Journal 13: 299–309.
  49. 49. Bragg K, Schlenk EA, Wolf G, Hoolahan S, Ren D, et al. (2012) Time out! Surveying surgical barriers. Nursing Management 43: 38–44.
  50. 50. Calland JF, Turrentine FE, Guerlain S, Bovbjerg V, Poole GR, et al. (2011) The surgical safety checklist: lessons learned during implementation. Am Surg 77: 1131–1137.
  51. 51. McDowell DS, McComb SA (2014) Safety Checklist Briefings: A Systematic Review of the Literature. AORN Journal 99: 125–137.e113.
  52. 52. Haynes AB, Weiser TG, Berry WR, Lipsitz SR, Breizat A-HS, et al. (2011) Changes in safety attitude and relationship to decreased postoperative morbidity and mortality following implementation of a checklist-based surgical safety intervention. BMJ Quality & Safety 20: 102–107.
  53. 53. Thomassen O, Espeland A, Softeland E, Lossius HM, Heltne JK, et al. (2011) Implementation of checklists in health care; learning from high-reliability organisations. Scand J Trauma Resusc Emerg Med 19: 53.
  54. 54. Shanafelt TD, Boone S, Tan L, Dyrbye L, Sotile W, et al. (2012) BUrnout and satisfaction with work-life balance among us physicians relative to the general us population. Archives of Internal Medicine 172: 1377–1385.
  55. 55. Morton LM, Cahill J, Hartge P (2006) Reporting Participation in Epidemiologic Studies: A Survey of Practice. American Journal of Epidemiology 163: 197–203.
  56. 56. Galea S, Tracy M (2007) Participation Rates in Epidemiologic Studies. Annals of Epidemiology 17: 643–653.
  57. 57. Ziegenfuss JY, Shah ND, Fan J, Van Houten HK, Deming JR, et al. (2012) Patient Characteristics of Provider Survey Respondents: No Evidence of Nonresponse Bias. Eval Health Prof 35: 507–516.
  58. 58. Perneger TV, Cullati S, Rudaz S, Agoritsas T, Schmidt RE, et al. (2014) Effect of numbering of return envelopes on participation, explicit refusals, and bias: experiment and meta-analysis. BMC Med Res Methodol 14: 6.
  59. 59. Rydenfält C, Ek Å, Larsson PA (2013) Safety checklist compliance and a false sense of safety: new directions for research. BMJ Quality & Safety.