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Correction: Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages

  • The PLOS ONE Staff

Correction: Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages

  • The PLOS ONE Staff
PLOS
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Figure 2 and its figure legend are incorrect. The authors have provided a corrected version here.

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Figure 2. Comparison of Akt/mTOR and ERK signaling pathways in wild-type and CatE−/−  macrophages.

(A) The cell lysates (100 µg protein for each) derived from wild-type (+/+) and CatE−/− macrophages (−/−) were subjected to SDS-PAGE followed by western blotting with specific antibodies to mTOR, p-mTOR, Akt, p-Akt(Thr308), p-Akt(Ser473), Erk, p-Erk1/2(Thr202/Tyr204), S-6, p-S6, AMPK, p-AMPK and actin. The data indicate the representative Western blotting of 3 independent experiments. (B) Densitometric analysis for the quantification of each protein in the cell lysate of both cell types. The arbitrary density unit was defined as the relative chemiluminescence intensity per mm2 measured by LAS1000. The data are indicated as the mean ± SD values from 3 independent experiments. *P < 0.05 for the indicated comparisons.

https://doi.org/10.1371/journal.pone.0082415.g002

Reference

  1. 1. Tsukuba T, Yanagawa M, Kadowaki T, Takii R, Okamoto Y, et al. (2013) Cathepsin E Deficiency Impairs Autophagic Proteolysis in Macrophages. PLoS ONE 8(12): e82415