As a result of mistakes in the typesetting process, there were errors in the Figure 4 legend in the PDF. A correct version of the legend is available below.
Figure 4. BOLL displays greater co-localisation with the meiosis marker SYCP3 than DAZL.
A) Triple immunofluorescence analysis of DAZL (green), BOLL (blue) and SYCP3 (red) in 14 and 17 week ovary. All BOLL+ germ cells also express SYCP3 (arrowheads), but only a few DAZL+ germ cell express SYCP3 (arrows). Unfilled arrows indicate the SYCP3-positive cells that express neither DAZL nor BOLL. The asterisk indicates a germ cell nest containing BOLL+SYCP3+, DAZL+SYCP3+ and DAZL+SYCP- germ cells in close proximity. Scale bars: 20µm. B) magnified image of germ cell nest marked with asterisk in A, showing neighboring germ cells expressing different combinations of DAZL, BOLL and SYCP3 expression; arrow denotes DAZL+SYCP3+ germ cell, arrowhead denotes BOLL+SYCP+ germ cell. C) Quantification of DAZL, BOLL and SYCP3 co-expression. ~69% of SYCP3+ cells also express BOLL+. This is significantly greater than the percentage of all the other co-expression patterns (n=3 14-17 week human fetal ovaries; ***p<0.001).
Citation: He J, Stewart K, Kinnell HL, Anderson RA, Childs AJ (2013) Correction: A Developmental Stage-Specific Switch from DAZL to BOLL Occurs during Fetal Oogenesis in Humans, but Not Mice. PLoS ONE 8(11): 10.1371/annotation/34304231-e54b-4080-af70-6f957f32d552. https://doi.org/10.1371/annotation/34304231-e54b-4080-af70-6f957f32d552
Published: November 14, 2013
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