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Correction: A Developmental Stage-Specific Switch from DAZL to BOLL Occurs during Fetal Oogenesis in Humans, but Not Mice

  • Jing He,
  • Kayleigh Stewart,
  • Hazel L. Kinnell,
  • Richard A. Anderson,
  • Andrew J. Childs

Correction: A Developmental Stage-Specific Switch from DAZL to BOLL Occurs during Fetal Oogenesis in Humans, but Not Mice

  • Jing He, 
  • Kayleigh Stewart, 
  • Hazel L. Kinnell, 
  • Richard A. Anderson, 
  • Andrew J. Childs
PLOS
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As a result of mistakes in the typesetting process, there were errors in the Figure 4 legend in the PDF. A correct version of the legend is available below.

Figure 4. BOLL displays greater co-localisation with the meiosis marker SYCP3 than DAZL.

A) Triple immunofluorescence analysis of DAZL (green), BOLL (blue) and SYCP3 (red) in 14 and 17 week ovary. All BOLL+ germ cells also express SYCP3 (arrowheads), but only a few DAZL+ germ cell express SYCP3 (arrows). Unfilled arrows indicate the SYCP3-positive cells that express neither DAZL nor BOLL. The asterisk indicates a germ cell nest containing BOLL+SYCP3+, DAZL+SYCP3+ and DAZL+SYCP- germ cells in close proximity. Scale bars: 20µm. B) magnified image of germ cell nest marked with asterisk in A, showing neighboring germ cells expressing different combinations of DAZL, BOLL and SYCP3 expression; arrow denotes DAZL+SYCP3+ germ cell, arrowhead denotes BOLL+SYCP+ germ cell. C) Quantification of DAZL, BOLL and SYCP3 co-expression. ~69% of SYCP3+ cells also express BOLL+. This is significantly greater than the percentage of all the other co-expression patterns (n=3 14-17 week human fetal ovaries; ***p<0.001).