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Open Access
Peer-reviewed
Research Article
A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren’s Syndrome
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Katherine James,
Affiliations Interdisciplinary Computing and Complex BioSystems Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
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Shereen Al-Ali,
Affiliations Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, Department of Biology, College of Science, University of Basrah, Basrah, Iraq
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Jessica Tarn,
Affiliation Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
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Simon J. Cockell,
Affiliation Bioinformatics Support Unit, Newcastle University, Newcastle upon Tyne, United Kingdom
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Colin S. Gillespie,
Affiliation School of Mathematics & Statistics, Newcastle University, Newcastle upon Tyne, United Kingdom
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Victoria Hindmarsh,
Affiliation Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom
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James Locke,
Affiliation Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
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Sheryl Mitchell,
Affiliation Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom
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Dennis Lendrem,
Affiliation Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
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Simon Bowman,
Affiliation Rheumatology Department, University Hospital Birmingham, Birmingham, United Kingdom
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Elizabeth Price,
Affiliation Great Western Hospitals NHS Foundation Trust, Swindon, United Kingdom
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Colin T. Pease,
Affiliation Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust, Leeds, United Kingdom
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Paul Emery,
Affiliation Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust, Leeds, United Kingdom
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Peter Lanyon,
Affiliation Nottingham University Hospital, Nottingham, United Kingdom
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John A. Hunter,
Affiliation Gartnavel General Hospital, Glasgow, United Kingdom
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Monica Gupta,
Affiliation Gartnavel General Hospital, Glasgow, United Kingdom
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Michele Bombardieri,
Affiliation Barts and the London NHS Trust & Barts and the London School of Medicine and Dentistry, London, United Kingdom
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Nurhan Sutcliffe,
Affiliation Barts and the London NHS Trust & Barts and the London School of Medicine and Dentistry, London, United Kingdom
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Costantino Pitzalis,
Affiliation Barts and the London NHS Trust & Barts and the London School of Medicine and Dentistry, London, United Kingdom
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John McLaren,
Affiliation NHS Fife, Whyteman’s Brae Hospital, Kirkcaldy, United Kingdom
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Annie Cooper,
Affiliations Royal Hampshire County Hospital, Winchester, United Kingdom, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom
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Marian Regan,
Affiliation Royal Derby Hospital, Derby, United Kingdom
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Ian Giles,
Affiliation University College London Hospitals NHS Foundation Trust, London, United Kingdom
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David Isenberg,
Affiliation University College London Hospitals NHS Foundation Trust, London, United Kingdom
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Vadivelu Saravanan,
Affiliation Queen Elizabeth Hospital, Gateshead, United Kingdom
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David Coady,
Affiliation Sunderland Royal Hospital, Sunderland, United Kingdom
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Bhaskar Dasgupta,
Affiliation Southend University Hospital, Southend, United Kingdom
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Neil McHugh,
Affiliation Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom
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Steven Young-Min,
Affiliation Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom
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Robert Moots,
Affiliation Aintree University Hospitals, Liverpool, United Kingdom
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Nagui Gendi,
Affiliation Basildon Hospital, Basildon, United Kingdom
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Mohammed Akil,
Affiliation Royal Hallamshire Hospital, Sheffield, United Kingdom
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Bridget Griffiths,
Affiliation Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom
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The UK Primary Sjögren’s Syndrome registry ,
¶The full UKPSSR collaborators list can be found in the Acknowledgments section.
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Anil Wipat,
Affiliation Interdisciplinary Computing and Complex BioSystems Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom
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Julia Newton,
Affiliations Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
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David E. Jones,
Affiliation Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
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John Isaacs,
Affiliations Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, National Institute for Health Research, Newcastle Biomedical Research Centre, Newcastle upon Tyne, United Kingdom
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Jennifer Hallinan,
Affiliations Interdisciplinary Computing and Complex BioSystems Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom, BioThink Pty Ltd, Brisbane, Australia
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Wan-Fai Ng
* E-mail: wan-fai.ng@newcastle.ac.uk
Affiliations Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, National Institute for Health Research, Newcastle Biomedical Research Centre, Newcastle upon Tyne, United Kingdom
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A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren’s Syndrome
- Katherine James,
- Shereen Al-Ali,
- Jessica Tarn,
- Simon J. Cockell,
- Colin S. Gillespie,
- Victoria Hindmarsh,
- James Locke,
- Sheryl Mitchell,
- Dennis Lendrem,
- Simon Bowman
- Published: December 22, 2015
- https://doi.org/10.1371/journal.pone.0143970