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Open Access
Peer-reviewed
Research Article
IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas
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Xin Huang,
Affiliation Department of Pediatrics, Division of Hematology, Oncology and Stem Cell Transplantation, New York Medical College, Valhalla, NY, United States of America
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Haein Park,
Affiliation Department of Pediatrics, Division of Hematology, Oncology and Stem Cell Transplantation, New York Medical College, Valhalla, NY, United States of America
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Joseph Greene,
Affiliation University of Minnesota College of Biological Sciences, Minneapolis, MN, United States of America
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James Pao ,
Contributed equally to this work with: James Pao, Erin Mulvey
Affiliation New York Medical College School of Medicine, Valhalla, NY, United States of America
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Erin Mulvey ,
Contributed equally to this work with: James Pao, Erin Mulvey
Affiliation New York Medical College School of Medicine, Valhalla, NY, United States of America
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Sophia X. Zhou,
Affiliation Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States of America
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Catherine M. Albert,
Affiliation Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, United States of America
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Fred Moy,
Affiliation Department of Pathology, New York Medical College, Valhalla, NY, United States of America
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Deepali Sachdev,
Affiliation Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States of America
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Douglas Yee,
Affiliation Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States of America
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Christoph Rader,
Affiliations Department of Cancer Biology, The Scripps Research Institute, Jupiter, FL, United States of America, Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL, United States of America
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Carl V. Hamby,
Affiliation Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, United States of America
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David M. Loeb,
Affiliation Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, United States of America
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Mitchell S. Cairo,
Affiliations Department of Pediatrics, Division of Hematology, Oncology and Stem Cell Transplantation, New York Medical College, Valhalla, NY, United States of America, Department of Pathology, New York Medical College, Valhalla, NY, United States of America, Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, United States of America, Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, United States of America, Department of Medicine, New York Medical College, Valhalla, NY, United States of America
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Xianzheng Zhou
* E-mail: xianzheng_zhou@nymc.edu
Affiliations Department of Pediatrics, Division of Hematology, Oncology and Stem Cell Transplantation, New York Medical College, Valhalla, NY, United States of America, Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, United States of America, Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, United States of America
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IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas
- Xin Huang,
- Haein Park,
- Joseph Greene,
- James Pao,
- Erin Mulvey,
- Sophia X. Zhou,
- Catherine M. Albert,
- Fred Moy,
- Deepali Sachdev,
- Douglas Yee
- Published: July 14, 2015
- https://doi.org/10.1371/journal.pone.0133152