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Open Access
Peer-reviewed
Research Article
Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial
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Steven F. L. van Lelyveld,
Affiliations Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Internal Medicine & Gastroenterology, Spaarne Gasthuis, Haarlem, The Netherlands
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Julia Drylewicz ,
Contributed equally to this work with: Julia Drylewicz, Maaike Krikke, Ellen M. Veel
Affiliation Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
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Maaike Krikke ,
Contributed equally to this work with: Julia Drylewicz, Maaike Krikke, Ellen M. Veel
Affiliation Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
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Ellen M. Veel ,
Contributed equally to this work with: Julia Drylewicz, Maaike Krikke, Ellen M. Veel
Affiliation Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
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Sigrid A. Otto,
Affiliation Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
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Clemens Richter,
Affiliation Department of Internal Medicine, Rijnstate Hospital, Arnhem, The Netherlands
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Robin Soetekouw,
Affiliation Department of Internal Medicine & Gastroenterology, Spaarne Gasthuis, Haarlem, The Netherlands
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Jan M. Prins,
Affiliation Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Kees Brinkman,
Affiliation Department of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
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Jan Willem Mulder,
Affiliation Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
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Frank Kroon,
Affiliation Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
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Ananja Middel,
Affiliation Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
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Jori Symons,
Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
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Annemarie M. J. Wensing,
Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
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Monique Nijhuis,
Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
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José A. M. Borghans,
Affiliation Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
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Kiki Tesselaar ,
* E-mail: k.tesselaar@umcutrecht.nl
¶‡ These authors also contributed equally to this work.
Affiliation Department of Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
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Andy I. M. Hoepelman ,
¶‡ These authors also contributed equally to this work.
Affiliation Department of Internal Medicine & Infectious Diseases, University Medical Center Utrecht, Utrecht, The Netherlands
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MIRS study group
¶The complete membership of the MIRS study group is provided in the Acknowledgments.
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Maraviroc Intensification of cART in Patients with Suboptimal Immunological Recovery: A 48-Week, Placebo-Controlled Randomized Trial
- Steven F. L. van Lelyveld,
- Julia Drylewicz,
- Maaike Krikke,
- Ellen M. Veel,
- Sigrid A. Otto,
- Clemens Richter,
- Robin Soetekouw,
- Jan M. Prins,
- Kees Brinkman,
- Jan Willem Mulder
- Published: July 24, 2015
- https://doi.org/10.1371/journal.pone.0132430