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Open Access
Peer-reviewed
Research Article
Stress-Induced Alternative Splice Forms of MDM2 and MDMX Modulate the p53-Pathway in Distinct Ways
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Aishwarya G. Jacob ,
Contributed equally to this work with: Aishwarya G. Jacob, Ravi K. Singh
Affiliations From the Center for Childhood Cancer at the Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, The Department of Pediatrics, and Molecular, Cellular and Developmental Biology (MCDB) program, The Ohio State University, Columbus, Ohio, United States of America, Center for RNA Biology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, United States of America
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Ravi K. Singh ,
Contributed equally to this work with: Aishwarya G. Jacob, Ravi K. Singh
Current address: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA
Affiliations From the Center for Childhood Cancer at the Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, The Department of Pediatrics, and Molecular, Cellular and Developmental Biology (MCDB) program, The Ohio State University, Columbus, Ohio, United States of America
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Daniel F. Comiskey Jr,
Affiliations From the Center for Childhood Cancer at the Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, The Department of Pediatrics, and Molecular, Cellular and Developmental Biology (MCDB) program, The Ohio State University, Columbus, Ohio, United States of America, Center for RNA Biology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, United States of America
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Matthew F. Rouhier,
Affiliation From the Center for Childhood Cancer at the Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America
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Fuad Mohammad,
Affiliations From the Center for Childhood Cancer at the Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, Center for RNA Biology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, United States of America
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Thomas W. Bebee,
Affiliations From the Center for Childhood Cancer at the Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, The Department of Pediatrics, and Molecular, Cellular and Developmental Biology (MCDB) program, The Ohio State University, Columbus, Ohio, United States of America
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Dawn S. Chandler
* E-mail: Dawn.Chandler@nationwidechildrens.org
Affiliations From the Center for Childhood Cancer at the Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, The Department of Pediatrics, and Molecular, Cellular and Developmental Biology (MCDB) program, The Ohio State University, Columbus, Ohio, United States of America, Center for RNA Biology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, United States of America
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Stress-Induced Alternative Splice Forms of MDM2 and MDMX Modulate the p53-Pathway in Distinct Ways
- Aishwarya G. Jacob,
- Ravi K. Singh,
- Daniel F. Comiskey Jr,
- Matthew F. Rouhier,
- Fuad Mohammad,
- Thomas W. Bebee,
- Dawn S. Chandler
- Published: August 8, 2014
- https://doi.org/10.1371/journal.pone.0104444