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Open Access
Peer-reviewed
Research Article
Hypoxia Increases Gefitinib-Resistant Lung Cancer Stem Cells through the Activation of Insulin-Like Growth Factor 1 Receptor
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Akiko Murakami ,
Contributed equally to this work with: Akiko Murakami, Fumiyuki Takahashi
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Fumiyuki Takahashi ,
Contributed equally to this work with: Akiko Murakami, Fumiyuki Takahashi
* E-mail: fumiyuki@dol.hi-ho.ne.jp
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Fariz Nurwidya,
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Isao Kobayashi,
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Kunihiko Minakata,
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Muneaki Hashimoto,
Affiliation Department of Molecular and Cellular Parasitology, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Takeshi Nara,
Affiliation Department of Molecular and Cellular Parasitology, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Motoyasu Kato,
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Ken Tajima,
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Naoko Shimada,
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Shin-ichiro Iwakami,
Affiliation Juntendo University Shizuoka Hospital, Shizuoka, Japan
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Mariko Moriyama,
Affiliation Pharmaceutical Research and technology institute, Kinki University, School of Medicine, Osaka, Japan
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Hiroyuki Moriyama,
Affiliation Pharmaceutical Research and technology institute, Kinki University, School of Medicine, Osaka, Japan
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Fumiaki Koizumi,
Affiliation Shien-Lab, National Cancer Center Hospital, Tokyo, Japan
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Kazuhisa Takahashi
Affiliations Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan, Research Institute for Diseases of Old Ages, Juntendo University, Graduate School of Medicine, Tokyo, Japan
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Hypoxia Increases Gefitinib-Resistant Lung Cancer Stem Cells through the Activation of Insulin-Like Growth Factor 1 Receptor
- Akiko Murakami,
- Fumiyuki Takahashi,
- Fariz Nurwidya,
- Isao Kobayashi,
- Kunihiko Minakata,
- Muneaki Hashimoto,
- Takeshi Nara,
- Motoyasu Kato,
- Ken Tajima,
- Naoko Shimada
- Published: January 28, 2014
- https://doi.org/10.1371/journal.pone.0086459