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Open Access
Peer-reviewed
Research Article
Elevated Levels of Plasma Phenylalanine in Schizophrenia: A Guanosine Triphosphate Cyclohydrolase-1 Metabolic Pathway Abnormality?
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Olaoluwa Okusaga,
Affiliations Mood and Anxiety Program, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America
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Olesja Muravitskaja,
Affiliation Mood and Anxiety Program, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Dietmar Fuchs,
Affiliation Division of Biological Chemistry, Biocenter Innsbruck Medical University, Innsbruck, Austria
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Ayesha Ashraf,
Affiliation Mood and Anxiety Program, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Sarah Hinman,
Affiliation Mood and Anxiety Program, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Ina Giegling,
Affiliation Section of Molecular and Clinical Neurobiology, Ludwig Maximilians University, Munich, Germany
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Annette M. Hartmann,
Affiliation Section of Molecular and Clinical Neurobiology, Ludwig Maximilians University, Munich, Germany
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Bettina Konte,
Affiliation Section of Molecular and Clinical Neurobiology, Ludwig Maximilians University, Munich, Germany
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Marion Friedl,
Affiliation Section of Molecular and Clinical Neurobiology, Ludwig Maximilians University, Munich, Germany
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Jason Schiffman,
Affiliation Department of Psychology, University of Maryland, Baltimore, Maryland, United States of America
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Elliot Hong,
Affiliation Maryland Psychiatric Research Center (MPRC), Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Gloria Reeves,
Affiliations Division of Child and Adolescent Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, University of Maryland Child and Adolescent Mental Health Innovations Center, Baltimore, Maryland, United States of America
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Maureen Groer,
Affiliation University of South Florida, Tampa, Florida, United States of America
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Robert Dantzer,
Affiliation The University of Texas, MD Anderson Cancer Center, Houston, Texas, United States of America
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Dan Rujescu ,
Contributed equally to this work with: Dan Rujescu, Teodor T. Postolache
Affiliations Section of Molecular and Clinical Neurobiology, Ludwig Maximilians University, Munich, Germany, Department of Psychiatry, University of Halle-Wittenberg, Halle, Germany
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Teodor T. Postolache
Contributed equally to this work with: Dan Rujescu, Teodor T. Postolache
* E-mail: tpostolache@psych.umaryland.edu
Affiliations Mood and Anxiety Program, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, University of Maryland Child and Adolescent Mental Health Innovations Center, Baltimore, Maryland, United States of America, VISN 5 Capitol Health Care Network Mental Illness Research Education and Clinical Center (MIRECC), Baltimore, Maryland, United States of America, VISN 19 MIRECC, Denver, Colorado, United States of America
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Elevated Levels of Plasma Phenylalanine in Schizophrenia: A Guanosine Triphosphate Cyclohydrolase-1 Metabolic Pathway Abnormality?
- Olaoluwa Okusaga,
- Olesja Muravitskaja,
- Dietmar Fuchs,
- Ayesha Ashraf,
- Sarah Hinman,
- Ina Giegling,
- Annette M. Hartmann,
- Bettina Konte,
- Marion Friedl,
- Jason Schiffman
- Published: January 21, 2014
- https://doi.org/10.1371/journal.pone.0085945