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Open Access
Peer-reviewed
Research Article
On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53
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Michal Bista ,
Contributed equally to this work with: Michal Bista, David Smithson
Affiliations Max-Planck Institute for Biochemistry, Martinsried, Germany, Department of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
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David Smithson ,
Contributed equally to this work with: Michal Bista, David Smithson
Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Aleksandra Pecak,
Affiliation Department of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
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Gabriella Salinas,
Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Katarzyna Pustelny,
Affiliation Department of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
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Jaeki Min,
Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Artur Pirog,
Affiliation Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
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Kristin Finch,
Affiliations Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Michal Zdzalik,
Affiliation Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
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Brett Waddell,
Affiliation Hartwell Center for Biotechnology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Benedykt Wladyka,
Affiliation Department of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
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Sylwia Kedracka-Krok,
Affiliations Department of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, Malopolska Centre of Biotechnology, Krakow, Poland
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Michael A. Dyer,
Affiliations Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
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Grzegorz Dubin,
Affiliations Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland, Malopolska Centre of Biotechnology, Krakow, Poland
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R. Kiplin Guy
* E-mail: kip.guy@stjude.org
Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53
- Michal Bista,
- David Smithson,
- Aleksandra Pecak,
- Gabriella Salinas,
- Katarzyna Pustelny,
- Jaeki Min,
- Artur Pirog,
- Kristin Finch,
- Michal Zdzalik,
- Brett Waddell
- Published: June 4, 2012
- https://doi.org/10.1371/journal.pone.0037518