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Open Access
Peer-reviewed
Research Article
Therapeutic Hemoglobin Levels after Gene Transfer in β-Thalassemia Mice and in Hematopoietic Cells of β-Thalassemia and Sickle Cells Disease Patients
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Laura Breda,
Affiliation Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, New York, United States of America
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Carla Casu,
Affiliation Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, New York, United States of America
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Sara Gardenghi,
Affiliation Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, New York, United States of America
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Nicoletta Bianchi,
Affiliation Dipartimento di Biochimica e Biologia Molecolare, Universita' di Ferrara, Ferrara, Italy
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Luca Cartegni,
Affiliation Department of Molecular Pharmacology and Chemistry, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
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Mohandas Narla,
Affiliation Red Cell Physiology Laboratory, New York Blood Center, New York, New York, United States of America
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Karina Yazdanbakhsh,
Affiliation Red Cell Physiology Laboratory, New York Blood Center, New York, New York, United States of America
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Marco Musso,
Affiliation Centro della Microcitemia e Anemie Congenite, Ospedali Galliera, Genova, Italy
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Deepa Manwani,
Affiliation Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, New York, United States of America
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Jane Little,
Affiliation Department of Medicine, Montefiore Medical Center, Bronx, New York, United States of America
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Lawrence B. Gardner,
Affiliation Department of Pharmacology, Langone Medical Center, New York University, New York, New York, United States of America
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Dorothy A. Kleinert,
Affiliation Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, New York, United States of America
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Eugenia Prus,
Affiliation Department of Hematology, Hadassah–Hebrew University Medical Center, Jerusalem, Israel
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Eitan Fibach,
Affiliation Department of Hematology, Hadassah–Hebrew University Medical Center, Jerusalem, Israel
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Robert W. Grady,
Affiliation Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, New York, United States of America
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Patricia J. Giardina,
Affiliation Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, New York, United States of America
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Roberto Gambari,
Affiliation Dipartimento di Biochimica e Biologia Molecolare, Universita' di Ferrara, Ferrara, Italy
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Stefano Rivella
* E-mail: str2010@med.cornell.edu
Affiliations Department of Pediatrics, Division of Hematology-Oncology, Children's Blood and Cancer Foundation Laboratories, Weill Cornell Medical College, New York, New York, United States of America, Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, New York, United States of America
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Therapeutic Hemoglobin Levels after Gene Transfer in β-Thalassemia Mice and in Hematopoietic Cells of β-Thalassemia and Sickle Cells Disease Patients
- Laura Breda,
- Carla Casu,
- Sara Gardenghi,
- Nicoletta Bianchi,
- Luca Cartegni,
- Mohandas Narla,
- Karina Yazdanbakhsh,
- Marco Musso,
- Deepa Manwani,
- Jane Little
- Published: March 27, 2012
- https://doi.org/10.1371/journal.pone.0032345