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Serum Angiopoietin-1 and -2 Levels Discriminate Cerebral Malaria from Uncomplicated Malaria and Predict Clinical Outcome in African Children

  • Fiona E. Lovegrove,

    Affiliation McLaughlin-Rotman Centre for Global Health, McLaughlin Centre for Molecular Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

  • Noppadon Tangpukdee,

    Affiliation Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  • Robert O. Opoka,

    Affiliation Department of Paediatrics and Child Health, Makerere University, Kampala, Uganda

  • Erin I. Lafferty,

    Affiliation McLaughlin-Rotman Centre for Global Health, McLaughlin Centre for Molecular Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

  • Nimerta Rajwans,

    Affiliation McLaughlin-Rotman Centre for Global Health, McLaughlin Centre for Molecular Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

  • Michael Hawkes,

    Affiliation McLaughlin-Rotman Centre for Global Health, McLaughlin Centre for Molecular Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

  • Srivicha Krudsood,

    Affiliation Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  • Sornchai Looareesuwan †,

    † Deceased.

    Affiliation Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

  • Chandy C. John,

    Affiliation Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America

  • W. Conrad Liles ,

    Contributed equally to this work with: W. Conrad Liles, Kevin C. Kain

    Affiliations McLaughlin-Rotman Centre for Global Health, McLaughlin Centre for Molecular Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada, Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

  • Kevin C. Kain

    Contributed equally to this work with: W. Conrad Liles, Kevin C. Kain

    kevin.kain@uhn.on.ca

    Affiliations McLaughlin-Rotman Centre for Global Health, McLaughlin Centre for Molecular Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada, Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

Serum Angiopoietin-1 and -2 Levels Discriminate Cerebral Malaria from Uncomplicated Malaria and Predict Clinical Outcome in African Children

  • Fiona E. Lovegrove, 
  • Noppadon Tangpukdee, 
  • Robert O. Opoka, 
  • Erin I. Lafferty, 
  • Nimerta Rajwans, 
  • Michael Hawkes, 
  • Srivicha Krudsood, 
  • Sornchai Looareesuwan, 
  • Chandy C. John, 
  • W. Conrad Liles
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