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S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mTOR Signaling and Microtubule Cytoskeleton

  • Chao Zhang ,

    Contributed equally to this work with: Chao Zhang, Na Yang

    Affiliation Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Na Yang ,

    Contributed equally to this work with: Chao Zhang, Na Yang

    Affiliation Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Chun-hao Yang,

    Affiliation Division of Organic Synthesis, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Hua-sheng Ding,

    Affiliation Division of Organic Synthesis, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Cheng Luo,

    Affiliation Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Yu Zhang,

    Affiliation Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Mao-jiang Wu,

    Affiliation Division of Organic Synthesis, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Xiong-wen Zhang,

    Affiliation Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Xu Shen,

    Affiliations Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, School of Pharmacy, East China University of Science and Technology, Shanghai, China

  • Hua-liang Jiang,

    Affiliations Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, School of Pharmacy, East China University of Science and Technology, Shanghai, China

  • Ling-hua Meng ,

    lhmeng@mail.shcnc.ac.cn (L-hM); jding@mail.shcnc.ac.cn (JD)

    Affiliation Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

  • Jian Ding

    lhmeng@mail.shcnc.ac.cn (L-hM); jding@mail.shcnc.ac.cn (JD)

    Affiliation Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mTOR Signaling and Microtubule Cytoskeleton

  • Chao Zhang, 
  • Na Yang, 
  • Chun-hao Yang, 
  • Hua-sheng Ding, 
  • Cheng Luo, 
  • Yu Zhang, 
  • Mao-jiang Wu, 
  • Xiong-wen Zhang, 
  • Xu Shen, 
  • Hua-liang Jiang
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