Haemodynamic effects of prenatal caffeine on the cardiovascular transition in ventilated preterm lambs
Heart rate (a) and peripheral oxygen saturation (b) in caffeine treated (grey dots) and control (black squares) lambs. The figure shows mean± SEM values at different time points during the experiment: before caffeine/ saline infusion; after caffeine/ saline infusion; before cord clamping (CC); after CC; before sustained inflation (SI); after SI; 5, 10, 15, 20, 25 and 30 minutes after ventilation onset. # indicates significant difference compared to “before CC” (grey within caffeine group, black within saline group). ^ indicates significant difference compared to “before SI” (grey within caffeine group, black within saline group).