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Haemodynamic effects of prenatal caffeine on the cardiovascular transition in ventilated preterm lambs

Fig 2

Left pulmonary artery blood flow (a) and carotid artery blood flow (b) in caffeine treated (grey dots) and control (black squares) lambs. The figure shows mean± SEM values at different time points during the experiment: before caffeine/ saline infusion; after caffeine/ saline infusion; before cord clamping (CC); after CC; before sustained inflation (SI); after SI; 5, 10, 15, 20, 25 and 30 minutes after ventilation onset. * indicates significant difference between two adjacent time points (grey within caffeine group, black within saline group). # indicates significant difference compared to “before CC” (grey within caffeine group, black within saline group). ^ indicates significant difference compared to “before SI” (grey within caffeine group, black within saline group).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0200572.g002