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Influence of citrate concentration on the activation of blood cells in an in vitro dialysis setup

Fig 2

Activation of complement, platelets, and leukocytes during in vitro dialysis.

(a) changes in platelet counts; (b) increase of soluble PF4 as marker of platelet activation; (c) release of C3a-desArg over time as marker of complement activation; (d) leukocyte activation, as indicated by MPO levels. Asterisks indicate significant (p < 0.05) changes of the respective parameters as compared to baseline levels; none of the parameters was significantly different between the groups.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0199204.g002