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Probing structural changes in single enveloped virus particles using nano-infrared spectroscopic imaging

Fig 3

Topography, near-field amplitude (A3) and phase (φ3) images of several influenza virus particles i-(a), after compound 136 interaction (15 min) i-(b), followed by acid exposure i-(c). ii-(a-b) shows a different set of virus particles at neutral pH ii-(a) and ii-(b) shows the particles after acid exposure following compound 136 incubation (1 hr.). Scale bar 100 nm.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0199112.g003