Association of renal hyperfiltration with incident proteinuria - A nationwide registry study
Fig 2
A reverse J-shaped association between estimated glomerular filtration rate (eGFR) slope and the adjusted hazard ratio (aHR) for incident proteinuria.
aHR was calculated with a Cox regression model adjusted for age, sex, smoking status, regular exercise, regular alcohol consumption, known history of diabetes and/or hypertension medication, body mass index, systolic blood pressure, fasting serum glucose, serum triglycerides, and serum high-density lipoprotein-cholesterol in subjects who had undergone health screening five or more times. The relationship between the eGFR slope and the aHR was evaluated with a generalized additive model. The shaded area represents the 95% confidence interval.