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Monitoring tumor response to the vascular disrupting agent CKD-516 in a rabbit VX2 intramuscular tumor model using PET/MRI: Simultaneous evaluation of vascular and metabolic parameters

Fig 3

Serial changes of PET/MRI parameters in control group.

(a) Axial T2-weighted images demonstrated target tumors with high signal intensity in bilateral paravertebral muscles. At 1-week follow-up, there were areas of high signal intensity within tumors on T2 weighted images, suggestive of necrosis (arrows). (b) DCE-MRI, (c) Ktrans map, (d) iAUC, (e) PET images and (f) fusion images.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0192706.g003