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Monitoring tumor response to the vascular disrupting agent CKD-516 in a rabbit VX2 intramuscular tumor model using PET/MRI: Simultaneous evaluation of vascular and metabolic parameters

Fig 2

Serial measurement of (a) Ktrans, (b) iAUC, (c) SUVmax, (d) SUVmean, (e) MTV and (f) TLG at different time points.

* is a significant change compared to the baseline.

Ktrans: volume transfer coefficient

iAUC: initial area under the gadolinium concentration-time curve until 60 seconds

SUV: standardized uptake value

MTV: metabolic tumor volume

TLG: total lesion glycolysis.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0192706.g002