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Experimental increase in baseline corticosterone level reduces oxidative damage and enhances innate immune response

Fig 2

Physiological effects of chronic CORT treatment.

The effects of CORT-implantation on (a) body mass, (b) hematocrit, (c) total antioxidant status, (d) uric acid, (e) total glutathione, (f) malondialdehyde, (g) hemagglutination, (h) hemolysis and (i) coccidian infestation in post-molting house sparrows. Sampling sessions: t0 –pre-treatment, t1, t2 and t3 –first, second and third post-treatment, respectively. Hematocrit was not measured during the pre-treatment sampling session (but see Materials and methods and Results), while coccidian load was only counted after the termination of the experiment. Mean ± 1 SE are shown throughout, except for panels (g) and (h) where median, inter-quartile range and range are plotted, and dots denote outliers. Body mass and hematocrit was measured for all birds at t1, t2 and t3, while samples sizes for oxidative stress and immunity variables are 27 at t1, 26 at t2 and 26 at t3.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0192701.g002