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Time-course evaluation of intestinal structural disorders in a porcine model of intra-abdominal hypertension by mechanical intestinal obstruction

Fig 8

Histopathological images of ileum samples (H&E, haematoxyline-eosin staining) in control (A-B) and experimental groups (C-H). (A and B) Villi with intact epithelium (Grade 0) and dilated lymphatic vessel at the tips of some villi (asterisk). (C) Small subepithelial space in some villi (Grade 1, arrow). (D) Villi with preserved epithelium (Grade 0). (E) Dilation in the lymphatic vessel (asterisk) and slight subepithelial vacuolization in some villi (arrow) without forming subepithelial space (Grade 1). (F and G) Villi with small subepithelial spaces (Grade 1). (H) Villi with large subepithelial spaces that exceed twice the enterocyte size (Grade 2).

Fig 8

doi: https://doi.org/10.1371/journal.pone.0191420.g008