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Time-course evaluation of intestinal structural disorders in a porcine model of intra-abdominal hypertension by mechanical intestinal obstruction

Fig 5

Representative images of the intestinal injury degree based on the guideline of P.O.Park [33, 34].

Normal mucosa (grade 0); subepithelial vacuolization and subepithelial space at the villi tips lower than the size of an enterocyte (grade 1); subepithelial space at the villi tips greater than the size of an enterocyte (grade 2); epithelial lifting extended along the villi sides (grade 3), denuded villi (grade 4), loss of villi (grade 5), crypt layer infarction (grade 6), transmucosal infarction (grade 7), and transmural infarction (grade 8). The grades 6, 7 and 8 were not observed in this study.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0191420.g005