Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors
Fig 3
Daily translocation of Gαz immunoreactivity.
Micrographs of coronal sections of the retina, labelled for Gαz (red) and centrin3 (green), a marker of the connecting cilium and the photoreceptor inner segment (IS). The representative immunofluorescent image shows that Gαz protein is abundant in photoreceptors where its subcellular localization is under daily regulation. Gαz immunoreactivity mainly occurs in the inner segment (IS) at ZT6 and in the outer segment (OS) at ZT18. The solid bars indicate the dark period. ONL, outer nuclear layer. Scale bar, 10 μm.