Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation
Time course of changes in the Defined Daily Dose of anti-hypertensive agents in the two groups is shown. Each treatment group was further divided into two groups at DDD baseline levels; those of DDD = 0 (43 cases in E-HD, 31in C-HD), and those of DDD >0 (97 cases in E-HD, 91 in C-HD). In cases of DDD = 0, there was a significant change in C-HD, while, no change was found in E-HD, respectively (repeated-measure ANOVA). In cases of DDD >0, there was a significant change in E-HD, while, no change was found in C-HD, respectively (repeated-measure ANOVA). *P<0.001. **P<0.05. E-HD, electrolyzed water HD; C-HD, conventional HD. Circle denotes outliers.