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Modulation of the endogenous omega-3 fatty acid and oxylipin profile in vivo—A comparison of the fat-1 transgenic mouse with C57BL/6 wildtype mice on an omega-3 fatty acid enriched diet

Table 1

Fatty acid profile in tissues.

Shown are relative amounts of EPA, DHA and ARA as well as the sum of n6-PUFA, n3-PUFA, MUFA and SFA in liver, kidney, spleen, colon and brain tissue in WT (WT-STD) and fat-1 mice after 30 days on a standard sunflower oil based diet and in WT mice on the same diet enriched with EPA and DHA (WT-STD+n3) during the course of the feeding period (day 7–45). Results of the statistical analyses for selected fatty acids during the course of the feeding with the n3-PUFA enriched diet as well as for WT and fat-1 mice after 30 days on the experimental diets are shown in S6+S7 Tables.

Table 1