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Modulation of the endogenous omega-3 fatty acid and oxylipin profile in vivo—A comparison of the fat-1 transgenic mouse with C57BL/6 wildtype mice on an omega-3 fatty acid enriched diet

Fig 1

Fatty acid profile in blood.

Shown are relative amounts of EPA, DHA and ARA as well as the relative distribution of n3- and n6-PUFA, MUFA and SFA in transgenic fat-1 mice and wild type animals (WT-STD) on a sunflower oil based diet, as well as in wild type mice on the same diet enriched with EPA and DHA (WT-STD+n3) during the course of the feeding period (45 days) in (A) whole blood, (B) plasma and (C) blood cells. Analytes that were below the limit of quantification are marked with a white filling in the diagram. Results of the statistical analyses for selected fatty acids during the course of the feeding with the n3-PUFA enriched diet as well as for WT and fat-1 mice after 30 days on the experimental diets are shown in S6+S7 Tables.

Fig 1