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Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

Fig 2

Cumulative SFS visualizations of the median non-CCDS region (a) and SCN1A (b). For both panels, the observed SFS (red) was calculated using a control cohort of 1,662 WGS samples and the expected SFS (black) was calculated using neutral theory.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0181604.g002