Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

Fig 1

Smoothed histogram of CCDS and non-CCDS Orion scores.

For visual clarity scores below -1 were removed, for a total of 996 CCDS scores and 989 non-CCDS scores. The scores were calculated using a control cohort of 1,662 WGS samples. The distributions differ significantly (Permuted Mann-Whitney U test P value: 0.001). The CCDS scores’ variance is 0.023 and the non-CCDS scores’ variance is 0.042.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0181604.g001