Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
Fig 3
Skin and liver expression of A-SAA in a mouse model of psoriasiform dermatitis.
C57BL/6 mice were treated daily during six days with imiquimod 5% cream (IMQ), with Vaseline (VAS) or were not treated (NT). (A) SAA1/2 and (B) SAA3 mRNA expression was determined by RT-qPCR. All data represent mean ± SEM relative expression to GAPDH. Statistical comparisons were performed using t test (*p<0.05; **p<0.01; ns, non-significant).