High-resolution physicochemical characterization of different intravenous immunoglobulin products
Fc glycosylation of IgG1 (A), IgG2/3 (B), IgG4 (C) and Fab (D) for different intravenous immunoglobulin products. Data are displayed as mean ± standard deviation (n = 3 technical replicates). Single lots of each product were analyzed prior to or after the expiration date: Pri-1 (22 months after), Pri-2 (2 months prior), and Pri-3 (28 months after); Oct-1 (5 months prior), Oct-2 (12 months after), and Oct-3 (24 months after); Gam-1 (6 months after), Gam-2 (36 months prior), and Gam-3 (24 months after). Gam, Gammagard lot; Oct, Octagam lot; Pri, Privigen lot.