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High-resolution physicochemical characterization of different intravenous immunoglobulin products

Fig 3

Relative abundance of IgG3 and IgG4 isotypes (A) and IgG4 half antibody (B) in different lots of intravenous immunoglobulin products. Data are displayed as mean ± standard deviation (n = 3 technical replicates). Single lots of each product were analyzed prior to or after the expiration date: Pri-1 (22 months after), Pri-2 (2 months prior), and Pri-3 (28 months after); Oct-1 (5 months prior), Oct-2 (12 months after), and Oct-3 (24 months after); Gam-1 (6 months after), Gam-2 (36 months prior), and Gam-3 (24 months after). Gam, Gammagard lot; Oct, Octagam lot; Pri, Privigen lot.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0181251.g003