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Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury

Fig 4

(A) Scatter plot of AEB for miR-122 measured in the serum of 4 healthy volunteers and 4 individuals after overdosing on acetaminophen. The dotted lines represent the mean assay (buffer) background ± 1 s.d.. (B) Correlation of concentration of miR-122 in the serum of patients determined using Simoa and PCR (r2 = 0.93; slope = 0.64).

Fig 4

doi: https://doi.org/10.1371/journal.pone.0179669.g004