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Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury

Fig 3

Plot of AEB determined using the assay in Fig 1 against concentration of calibrators for miR-122 (circles) and the same molecule with a single base mismatch at the 9th position (squares) spiked into buffer.

The sequences of these two molecules are shown in S2 Table. Error bars (±1 s.d.) based on duplicate measurements are smaller than the size of the data point.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0179669.g003