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An R-CaMP1.07 reporter mouse for cell-type-specific expression of a sensitive red fluorescent calcium indicator

Fig 3

Layer-specific R-CaMP1.07 expression and calcium transients in vivo.

A, Large field-of-view two-photon images in S1 cortex for the four different mouse lines expressing R-CaMP1.07. In L4-R-CaMP1.07 mice the barrels and septa in S1 cortex are clearly discernible. B, Example spontaneous R-CaMP1.07 calcium transients measured in awake mice of the corresponding mouse lines. Traces for three example cells (marked) are shown for each imaging field.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0179460.g003