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Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer

Fig 3

Systematic motif detection identifies oncogenic TFBS gain-of-binding events.

(a) Analysis pipeline for detecting motifs from wildtype and mutant allele sequences. (b) Histogram of delta values for WGS SNV allele pairs after filtering to keep only allele pairs with at least one motif score of absolute value ≥ 2.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0174032.g003