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Biophysical comparison of ATP-driven proton pumping mechanisms suggests a kinetic advantage for the rotary process depending on coupling ratio

Fig 3

Kinetic models of all possible proton transport orders for ATP-driven H+ pump mechanisms based on one of six possible nucleotide and phosphate binding/unbinding sequences in the ATP-driven proton pumping cycle.

Coupling ratio of 3:1 H+:ATP is shown here. See S1 File for 2:1 coupling ratio. Results are qualitatively similar for other event orders. See S1 File and Fig 4(b).

Fig 3