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Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors

Fig 2

The expression of Wfs1 and Drd1a in the mouse intercalated amygdala and in its putative avian homologue, StC, in chick.

The expression of Wfs1 and Drd1a in the mouse intercalated amygdala and in its putative avian homologue, StC, in chick. A, B–in situ hybridization on coronal sections of the mouse brain. C, D–immunohistochemistry on coronal sections of the mouse brain. E, F–in situ hybridization on the coronal sections of the chick brain. The intercalated nuclei of the amygdala (arrowheads) are expressing both Wfs1 and Drd1a in mouse brain (A, B). Wfs1 and D1 proteins are both strongly expressed in the intercalated nuclei (C, D). The insets in C and D show closer view on the intercalated nucleus between the BL and claustrum-endopiriform formation. In chick brain, the StC is expressing both Wfs1 and Drd1a. For abbreviations, see list. Scale bar is 100 μm in A-D and 1 mm in E-F.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0172825.g002