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Two-Photon Microscopy Analysis of Gold Nanoparticle Uptake in 3D Cell Spheroids

Fig 3

Sample Two-photon images of HCT116 cell spheroids used for estimation of AuNP uptake in cell spheroids.

The images in the top row are obtained from a control spheroid while the images in the bottom row are obtained from a cell spheroid incubated with AuNP. The green emission is due to TurboGFP expressed by the HCT116 cells while the red emission is from the AuNP. (Scale bar: 50μm).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0167548.g003