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A Conditioned Behavioral Paradigm for Assessing Onset and Lasting Tinnitus in Rats

Fig 7

Licking rates during silent trials prior to injections (post-exposure week 8), as well as 3 hours and 5 days following saline (A) or salicylate (B) injections.

After saline injections, no changes in licking rate were observed. Three hours following salicylate injections, however, all nine animals increased licking behavior during silent trials, though most robustly following high-frequency narrowband sound trials. The licking rates during silent trials returned to pre-injection levels by 5 days post-injection.

Fig 7

doi: https://doi.org/10.1371/journal.pone.0166346.g007