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Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling

Fig 2

ASD pathway network.

Pathways are grouped vertically under two classes, Disease and Function. The color of each node within the groupings represents the p-value of that pathway. The size of each node represents the number of ASD genes in that pathway. Interactions between pairs of pathways are indicated by edges. The pathway-pathway interaction matrix is in S3 Table.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0153329.g002