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MiRComb: An R Package to Analyse miRNA-mRNA Interactions. Examples across Five Digestive Cancers

Fig 6

Clustering and Principal Components Analysis of the five digestive cancers.

Computations are based on the correlation coefficients of the 106.426 miRNA-mRNA pairs that are expressed across all five cancer data sets. A) Heatmap showing the centers of the different clusters. Values represent the mean of the Pearson correlation coefficient of the miRNA-mRNA pairs that fall into the cluster. B) Principal Components Analysis (based on correlation matrix) of the Pearson correlation coefficient of the miRNA-mRNA pairs from the five digestive cancer data sets.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0151127.g006