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A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice

Fig 1

Behavioral Test Battery.

Mice were tested in a behavioral test battery consisting of (top panel, from left to right): forced alternation (Y-maze), novel object recognition, Morris water maze, radial arm water maze, and spontaneous alternation (Y-maze) over a period of 8 weeks. Top panel: Behavioral tests conducted in the study. Middle panel: Timeline of tests. Bottom panel: Trials conducted per behavioral test. Tests were conducted in the order of increasing invasiveness. The spontaneous alternation test was performed last to maximize the interval to the forced alternation test, which utilized the same maze.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0147733.g001