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How to Establish and Follow up a Large Prospective Cohort Study in the 21st Century - Lessons from UK COSMOS

Fig 2

Characteristics of participants from two major recruitment campaigns to the UK COSMOS study (Phases 2 and 7).

Legend: Blue bars represent Phase 2, red bars represent Phase 7. Fig 2 Footnotes: Phase 2 used a mobile phone subscriber sampling frame, letter invitation, web-based consent, registration, and questionnaire and a prize draw incentive, and recruited N = 67,793. Phase 7 used an electoral register sampling frame, letter invitation, web-based consent, registration, and questionnaire and a gift voucher incentive, and recruited N = 36,316. Together Phases 2 and 7 recruited N = 104,109. The profile of participants presented here is based on N = 67627 from Phase 2 and N = 36218 from Phase 7, i.e. excluding 264 withdrawals. With the exception of socio-economic classification, the percentages calculated exclude Missing from the denominator. N for missing are as follows: Phase 2: Sex N = 290, Age group N = 306, Ethnicity N = 9205, Highest Educational Qualification N = 9124, Smoking N = 8404; Phase 7: Sex N = 2, Age group N = 9, Ethnicity N = 5135, Highest Educational Qualification N = 5083, Smoking N = 4760. For socio-economic classification Missing are included in the Not classified category, which also contains people who never worked or were long-term unemployed and therefore could not be assigned a classification based on occupation.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0131521.g002