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Comprehensive In Vitro Toxicity Testing of a Panel of Representative Oxide Nanomaterials: First Steps towards an Intelligent Testing Strategy

Fig 1

Methodology applied for the in vitro toxicity assessment.

Ten different assays were used for the evaluation of cytotoxicity (resazurin, NRU, WST-1, WST-8, LDH and CFE), embryotoxicity (EST), epithelial integrity (TEER), cytokine secretion (ELISA) and oxidative stress (DCF) on twelve different cellular systems.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0127174.g001