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Prevalence and Characterization of Murine Leukemia Virus Contamination in Human Cell Lines

Fig 4

Neighbor joining tree of the MLV sequences of the first round PCR products.

The chart demonstrates the relationship of the MLV sequences generated with the outer primer pair of the detection PCR reaction. The alignment and the tree construction were performed with the MEGA6 software. Three major groups of MLV subtypes can be identified. The scale bar represents the number of nucleotide substitutions per site. * Sequences obtained from the NCBI sequence database.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0125622.g004