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Early Maternal Alcohol Consumption Alters Hippocampal DNA Methylation, Gene Expression and Volume in a Mouse Model

Fig 3

DNA methylation levels of CpG islands of five candidate genes in control and ethanol-exposed offspring.

DNA methylation levels of CpG islands in Vmn2r64 [A: upstream CpG island (1) and B: CpG island in gene-body (2)], Olfr110 (C, upstream), Vpreb2 (D, in gene-body), and Olfr601 (E, in gene-body) in hippocampus (HC) and Olfr601 (F, in gene-body) in main olfactory epithelium (MOE). Each dot represents an average of methylation percent of clones in a particular CpG island from individual control or ethanol-exposed (EtOH) male offspring (P28).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0124931.g003