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Analysis of Antibody Aggregate Content at Extremely High Concentrations Using Sedimentation Velocity with a Novel Interference Optics

Fig 5

Influence of the frictional ratio on a global fit.

Sedimentation velocity experiment of antibody was conducted on the Aida ultracentrifuge at 25,000 rpm, 20°C. The c(s) distributions of data fits applying different frictional ratios are shown. Sedimentation coefficient and relative content of putative dimers are indicated.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0120820.g005