Analysis of Structural Flexibility of Damaged DNA Using Thiol-Tethered Oligonucleotide Duplexes
Fig 7
Effect of the linker length on the rate of the disulfide bond formation.
(A) Pt-6 (C4) (open circles) and Pt-6 (C3) (filled circles); (B) AP-6 (C4) (open squares) and AP-6 (C3) (filled squares); (C) 64–6 (C4) (open triangles) and 64–6 (C3) (filled triangles). The dashed and continuous lines represent the decrease of the starting materials and the increase of the cross-linked products, respectively, and the standard errors are shown. The curve fitting was performed with the Origin 9.1 software, and the kinetic constants for the product formation are listed in Table 1.